Fame Podcast Host
Mark Jacobstein is the co-founder of Jimini Health and the host of Neural Compass, a podcast dedicated to charting the future of AI and mental health for builders, decision-makers, and clinicians. He leads conversations that occupy the high-value gap between consumer wellness and technical developer content, focusing on how AI is reshaping behavioral health care.
With thirty years of experience building companies at the forefront of technology, Mark founded the world's first online fantasy sports business and later led mobile VOIP pioneer iSkoot to its acquisition by Qualcomm. His extensive career includes serving as the "adult supervision" for Sam Altman at Loopt and co-founding the Sequoia and Kleiner Perkins-backed mobile games pioneer Digital Chocolate.
Mark previously served as the Chief User Engagement Officer at Guardant Health through its IPO and as the CBO for the AI-driven biotech Immunai. In addition to his work at Jimini Health, he is the co-founder of Near Horizon, a venture builder that partners with entrepreneurs to launch AI-powered companies.
Ask me
- 1
How has your long-term experience building companies shaped your ability to distinguish between genuine technological changes and temporary "hype"?
- 2
Why is this gap between consumer wellness and technical developer content so critical for the future of behavioral health?
- 3
What are the most significant "frictions" encountered when trying to move from technical potential to real-world clinical implementation in the LLM for the mental health world?
- 4
Can you expound on what society risks if we get the integration of AI and behavioral health care wrong?
- 5
What are the challenges of building "AI-powered" companies that must also remain anchored in rigorous clinical evidence?
- 6
Can you talk about your key takeaways from your past leadership experiences that influence your work today?
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